Just make sure to have only the mods you actually use rather than abunch o installed mods that you used once or never at all, the game really suffers from loading huge textures(even if honestly it never happened again to me since i edited the exe), especially if png(dds would be the right choice but we're dicks and keep using png and jpg lol).
Diegorborges about my Valo fix: "Now all of you must have your slrr folder like this: C:/BIGBOSSisMYlordANDiamHISbitch/SLRR LOL"