You have to make a new save everytime you add or remove a mod, it'll crash if you removed a mod after making your save(that happens with every slr version)
Added 1 minute later:
Anyways we have specific areas for this kind of questions, try to use them the next time 😛
1 - /d/4-i-ve-got-a-question-and-i-want-to-create-a-thread&n=last#bottom
2 - /d/312-fixes-gamecrashes-other-help&n=last#bottom